Translational control in germline stem cell development
نویسندگان
چکیده
منابع مشابه
Translational control in germline stem cell development
Stem cells give rise to tissues and organs during development and maintain their integrity during adulthood. They have the potential to self-renew or differentiate at each division. To ensure proper organ growth and homeostasis, self-renewal versus differentiation decisions need to be tightly controlled. Systematic genetic studies in Drosophila melanogaster are revealing extensive regulatory ne...
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The piRNA pathway plays an important role in maintaining genome stability in the germ line by silencing transposable elements (TEs) from fly to mammals. As a highly conserved piRNA pathway component, Piwi is widely expressed in both germ cells and somatic cells in the Drosophila ovary and is required for piRNA production in both cell types. In addition to its known role in somatic cap cells to ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2014
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.201407102